Prosilico was founded by ex-AstraZeneca pharmacokineticist, PhD and Associate Professor in biopharmaceutics/pharmacokinetics and clinical psychologist Urban Fagerholm. He has a wide preclinical and clinical experience from 30 years in the pharmaceutical industry (AstraZeneca 1997-2013) and academia (Uppsala University), and has focused on prediction methodology, physiological models, mechanisms, analyses and strategies in the ADME/PK-field. In 2009, he was nominated International Educator of the Year and named member of Top 100 Professionals of the Year. He has published more than 40 scientific papers and book chapters and two popular science books.

Computational chemist and ex-manager in pharmaceutical R&D at AstraZeneca Sven Hellberg joined Prosilico in January 2016. Sven is highly experienced with 30+ years in QSAR, compound design and drug discovery. His skills and experiences include molecular modeling, pharmacophores, docking, structure-based design, fragment evolution, hit finding, lead identification, lead optimization, project leadership, project leader (including Lean Sigma), chemometrics, experimental design, machine learning, pattern recognition, coaching and team building. Sven a strong personal track record of delivery, and his foremost personal strengths are creativity, analytical and strategic thinking. He has been leader of the science forums for medicinal chemistry and compound design, and has excellent scientific track record with 50 scientific journal publications and 86 patent publications.

Ola Spjuth, PhD and Associate Professor in pharmaceutical bioinformatics at Uppsala University and expert in predictive modeling and big data analysis joined Prosilico in 2018. Ola was previous co-director at the UPPMAX high performance computing center at Uppsala University, and Head of the bioinformatics compute and storage facility at Science for Life Laboratory in Sweden. He has an excellent scientific track record with more than 100 scientific publications.