Explore ANDROMEDA by Prosilico

Extensively validated human clinical ADME/PK prediction, simulation and optimization software with higher accuracy than laboratory methods.


Experience & progress

We are motivated by a strong and sincere willingness to drive continuous improvement and renewal within ADME/PK science. We believe that a technology shift and significant quality improvements are within reach. Together we form a group of highly merited scientists with a long experience from the pharmaceutical industry, university and IT-development.


ADME/PK-prediction software with predictive power

Our software ANDROMEDA by Prosilico produces high quality in silico estimates of human clinical ADME/PK of modern drug candidates (for which standard laboratory methods have limited applicability) at a low cost. Our approach is firmly based on the assumption that clinical data is the best and most relevant source of human ADME/PK information.

The software has been carefully validated in a multitude of ways. We have also performed successful benchmarking vs alternative methods (in vitro and animal models). Median prediction errors are generally within 2- to 3-fold. Scientific publications and White paper are available to support our claims.

Make you feel good about it

You can rely on the fact that the human clinical ADME/PK parameters you get are the result of validated and relevant methods. The predictive power increases the likelihood that your compounds will have the desired ADME/PK properties in man and that clinical studies will be safe and planned for success. As a bonus you will also help to avoid unnecessary experiments in animals and reduce environmental emissions.

The latest news and publications


ANDROMEDA by Prosilico outperforms laboratory methods

In 49 study comparisons, ANDROMEDA by Prosilico outperformed laboratory methods in 74 % of cases…

PROSILICO participates in the planned SciLifeLab PULSE cofund postdoctoral programme

PROSILICO participates in the planned SciLifeLab PULSE cofund postdoctoral programme SciLifeLab has the ambition to…
Scientific publications

In silico prediction of human clinical pharmacokinetics with ANDROMEDA by Prosilico: Predictions for an established benchmarking data set, a modern small drug data set, and a comparison with laboratory methods

Fagerholm, Hellberg, Alvarsson, Spjuth. Altern Lab Anim. 51:39-54, 2023. https://journals.sagepub.com/doi/abs/10.1177/02611929221148447?journalCode=atla