3 October 2022
An analysis of laboratory variability and thresholds for human in vitro ADME/PK methods
Fagerholm. BioRxiv September 28, 2022. https://www.biorxiv.org/content/10.1101/2022.09.27.509731v1
28 September 2022
In vitro to in vivo pharmacokinetic translation guidance
Fagerholm. BioRxiv September 28, 2022. https://www.biorxiv.org/content/10.1101/2022.09.26.509470v1
27 September 2022
Investigation of Molecular Weights and Pharmacokinetic Characteristics of Older and Modern Small Drugs
Fagerholm. BioRxiv September 27, 2022. https://www.biorxiv.org/content/10.1101/2022.09.21.508888v1
24 September 2022
Prediction of Biopharmaceutical Characteristics of PROTACs using the ANDROMEDA by Prosilico Software
Fagerholm, Hellberg, Alvarsson and Spjuth. BioRxiv September 24, 2022. https://www.biorxiv.org/content/10.1101/2022.09.22.509053v1
17 August 2022
In silico predictions of the gastrointestinal uptake of macrocycles in man using conformal prediction methodology
Fagerholm, Hellberg, Alvarsson and Spjuth. J Pharm Sci. May 2022. https://pubmed.ncbi.nlm.nih.gov/35605685/
17 August 2022
The impact of reference data selection for the prediction accuracy of intrinsic hepatic metabolic clearance
Fagerholm, Spjuth and Hellberg. J Pharm Sci. July 2022. https://pubmed.ncbi.nlm.nih.gov/35793746/
17 August 2022
Comparison between lab variability and in silico prediction errors for the unbound fraction of drugs in human plasma
Fagerholm, Spjuth & Hellberg. Xenobiot. 51:1095-1100, 2021. https://www.tandfonline.com/doi/full/10.1080/00498254.2021.1964044
17 August 2022
In silico prediction of volume of distribution of drugs in man using conformal prediction performs on par with animal data-based models
Fagerholm, Hellberg, Alvarsson, Arvidsson McShane and Spjuth. Xenobiot. 51:1366-1371, 2021. https://www.tandfonline.com/doi/full/10.1080/00498254.2021.2011471
