Scientific publications 22 May 2023 Prediction of the human pharmacokinetics of 30 modern antibiotics using the ANDROMEDA software Fagerholm U, Hellberg S, Alvarsson J, Spjuth O. bioRxiv, March 2023.https://www.biorxiv.org/content/10.1101/2023.03.28.534601v1 Urban Fagerholm
News 21 March 2023 ANDROMEDA by Prosilico outperforms laboratory methods In 49 study comparisons, ANDROMEDA by Prosilico outperformed laboratory methods in 74 % of cases… Urban Fagerholm
News 21 March 2023 PROSILICO participates in the planned SciLifeLab PULSE cofund postdoctoral programme PROSILICO participates in the planned SciLifeLab PULSE cofund postdoctoral programme SciLifeLab has the ambition to… Urban Fagerholm
Scientific publications 21 March 2023 In silico prediction of human clinical pharmacokinetics with ANDROMEDA by Prosilico: Predictions for an established benchmarking data set, a modern small drug data set, and a comparison with laboratory methods Fagerholm, Hellberg, Alvarsson, Spjuth. Altern Lab Anim. 51:39-54, 2023. https://journals.sagepub.com/doi/abs/10.1177/02611929221148447?journalCode=atla Urban Fagerholm
Scientific publications 21 March 2023 Comparing in silico and in vitro methods for classification of BCS II and CYP3A4 and MDR-1 substrate specificity Fagerholm. BioRxiv December 15, 2022.https://www.biorxiv.org/content/10.1101/2022.12.13.520246v1 Urban Fagerholm
Scientific publications 21 March 2023 Predicting the influence of fat food intake on the absorption and systemic exposure of modern small drugs using ANDROMEDA by Prosilico software Fagerholm, Hellberg, Alvarsson, Spjuth. BioRxiv December 8, 2022.https://www.biorxiv.org/content/10.1101/2022.12.05.519072v1 Urban Fagerholm
Scientific publications 21 November 2022 Evaluation of the reliability and applicability of human unbound brain-to-plasma concentration ratios Fagerholm. BioRxiv November 21, 2022.https://www.biorxiv.org/content/10.1101/2022.11.14.516429v1 Urban Fagerholm
Scientific publications 14 November 2022 Validation of predicted conformal intervals for prediction of human clinical pharmacokinetics Fagerholm, Alvarsson, Hellberg, Spjuth. BioRxiv November 14, 2022. https://www.biorxiv.org/content/10.1101/2022.11.10.515917v1 Urban Fagerholm
News 14 November 2022 New article and ANDROMEDA milestone- Successful validation Validation of predicted conformal intervals for prediction of human clinical pharmacokinetics https://www.biorxiv.org/content/10.1101/2022.11.10.515917v1 Urban Fagerholm
Scientific publications 10 October 2022 ANDROMEDA by Prosilico software successfully predicts human clinical pharmacokinetics of 70 drugs out of reach for in vitro methods Fagerholm, Hellberg, Alvarsson, Spjuth. BioRxiv October 7, 2022. https://www.biorxiv.org/content/10.1101/2022.10.05.511015v1 Urban Fagerholm