News 14 September 2022 PROSILICO to present at SUP-meeting in Uppsala https://sup-meeting.se/ Urban Fagerholm
News 17 August 2022 September 1, 2022 – New accepted manuscript We are proud to announce that our manuscript "In silico prediction of human clinical pharmacokinetics… Urban Fagerholm
News 17 August 2022 August 30-31 2022 – PROSILICO will attend 1st Nordic Conference on Computational Chemistry in Gothenburg, Sweden PROSILICO will attend 1st Nordic Conference on Computational Chemistry August 30-31 2022 in Gothenburg, Sweden,… Urban Fagerholm
News 17 August 2022 April 27-28 2022 – PROSILICO attended 3rd Swedish Medicinal Chemistry Symposium in Stockholm PROSILICO attended 3rd Swedish Medicinal Chemistry Symposium in Stockholm April 27-28 2022 and gave pitch… Urban Fagerholm
Scientific publications 17 August 2022 Using the ANDROMEDA by Prosilico software for prediction of the human pharmacokinetics of 4 compounds of natural origin – colistin, curucumin, UCN-01 and voclosporin Fagerholm, Hellberg, Alvarsson and Spjuth. Biorxiv August 17, 2022. https://www.biorxiv.org/content/10.1101/2022.08.17.504228v1 Urban Fagerholm
Scientific publications 17 August 2022 In silico predictions of the gastrointestinal uptake of macrocycles in man using conformal prediction methodology Fagerholm, Hellberg, Alvarsson and Spjuth. J Pharm Sci. May 2022. https://pubmed.ncbi.nlm.nih.gov/35605685/ Urban Fagerholm
Scientific publications 17 August 2022 The impact of reference data selection for the prediction accuracy of intrinsic hepatic metabolic clearance Fagerholm, Spjuth and Hellberg. J Pharm Sci. July 2022. https://pubmed.ncbi.nlm.nih.gov/35793746/ Urban Fagerholm
Scientific publications 17 August 2022 In silico predictions of the human pharmacokinetics/toxicokinetics of 65 chemicals from various classes using conformal prediction methodology Fagerholm, Hellberg, Alvarsson and Spjuth. Xenobiot. 51:1366-1371, 2022. https://www.tandfonline.com/doi/abs/10.1080/00498254.2022.2049397 Urban Fagerholm
Scientific publications 17 August 2022 Comparison between lab variability and in silico prediction errors for the unbound fraction of drugs in human plasma Fagerholm, Spjuth & Hellberg. Xenobiot. 51:1095-1100, 2021. https://www.tandfonline.com/doi/full/10.1080/00498254.2021.1964044 Urban Fagerholm
Scientific publications 17 August 2022 In silico prediction of volume of distribution of drugs in man using conformal prediction performs on par with animal data-based models Fagerholm, Hellberg, Alvarsson, Arvidsson McShane and Spjuth. Xenobiot. 51:1366-1371, 2021. https://www.tandfonline.com/doi/full/10.1080/00498254.2021.2011471 Urban Fagerholm