Scientific publications 21 March 2023 Comparing in silico and in vitro methods for classification of BCS II and CYP3A4 and MDR-1 substrate specificity Fagerholm. BioRxiv December 15, 2022.https://www.biorxiv.org/content/10.1101/2022.12.13.520246v1 Urban Fagerholm
Scientific publications 21 March 2023 Predicting the influence of fat food intake on the absorption and systemic exposure of modern small drugs using ANDROMEDA by Prosilico software Fagerholm, Hellberg, Alvarsson, Spjuth. BioRxiv December 8, 2022.https://www.biorxiv.org/content/10.1101/2022.12.05.519072v1 Urban Fagerholm
Scientific publications 21 November 2022 Evaluation of the reliability and applicability of human unbound brain-to-plasma concentration ratios Fagerholm. BioRxiv November 21, 2022.https://www.biorxiv.org/content/10.1101/2022.11.14.516429v1 Urban Fagerholm
Scientific publications 14 November 2022 Validation of predicted conformal intervals for prediction of human clinical pharmacokinetics Fagerholm, Alvarsson, Hellberg, Spjuth. BioRxiv November 14, 2022. https://www.biorxiv.org/content/10.1101/2022.11.10.515917v1 Urban Fagerholm
News 14 November 2022 New article and ANDROMEDA milestone- Successful validation Validation of predicted conformal intervals for prediction of human clinical pharmacokinetics https://www.biorxiv.org/content/10.1101/2022.11.10.515917v1 Urban Fagerholm
Scientific publications 10 October 2022 ANDROMEDA by Prosilico software successfully predicts human clinical pharmacokinetics of 70 drugs out of reach for in vitro methods Fagerholm, Hellberg, Alvarsson, Spjuth. BioRxiv October 7, 2022. https://www.biorxiv.org/content/10.1101/2022.10.05.511015v1 Urban Fagerholm
News 10 October 2022 New article – Successful use of ANDROMEDA in cases where labs fail ANDROMEDA by Prosilico software successfully predicts human clinical pharmacokinetics of 70 drugs out of reach… Urban Fagerholm
News 3 October 2022 Steps in the right direction! FDA Modernization Act - The bill defines “nonclinical tests or studies ” as a test… Urban Fagerholm
Scientific publications 3 October 2022 Prediction and Classification of the Uptake and Disposition of Antidepressants and New CNS-Active Drugs in the Human Brain using the ANDROMEDA by Prosilico Software and Brainavailability-Matrix Fagerholm, Hellberg, Alvarsson, Spjuth. BioRxiv September 30, 2022. https://www.biorxiv.org/content/10.1101/2022.09.28.509936v1 Urban Fagerholm
Scientific publications 3 October 2022 An analysis of laboratory variability and thresholds for human in vitro ADME/PK methods Fagerholm. BioRxiv September 28, 2022. https://www.biorxiv.org/content/10.1101/2022.09.27.509731v1 Urban Fagerholm