17 August 2022
Comparison between lab variability and in silico prediction errors for the unbound fraction of drugs in human plasma
Fagerholm, Spjuth & Hellberg. Xenobiot. 51:1095-1100, 2021. https://www.tandfonline.com/doi/full/10.1080/00498254.2021.1964044
17 August 2022
In silico prediction of volume of distribution of drugs in man using conformal prediction performs on par with animal data-based models
Fagerholm, Hellberg, Alvarsson, Arvidsson McShane and Spjuth. Xenobiot. 51:1366-1371, 2021. https://www.tandfonline.com/doi/full/10.1080/00498254.2021.2011471
17 August 2022
Advances in predictions of oral bioavailability of candidate drugs in man with new machine learning methodology
Fagerholm, Hellberg and Spjuth. Molecules 26:2572, 2021. https://pubmed.ncbi.nlm.nih.gov/33925103/
17 August 2022
Authority publications about reduction of animal testing
Netherlands initiative to reduce animal testing https://english.ncadierproevenbeleid.nl/latest/news/16/12/15/ncad-opinion-transition-to-non-animal-research FDAs initiative to reduce animal testing https://www.fdanews.com/articles/182663-congress-pushes-for-in-silico-trials-modeling
